Research

Biomimetic Fabrication of Nanomaterials

Our group aims to address multiple challenges in developing functional nanomaterials for biological applications, such as identifying structure-activity relationships, mimicking cellular complexity and compartmentalization, or the directional reconstitution of biomolecules. To accomplish this goal, our team is pursuing novel biomimetic strategies involving rapid screening of functional nanomaterials, formation and remodeling of artificial cells, and preparation of bioinspired nanoreactors.

Chemical Tools for Biology and Medicine

Our group is developing new chemical tools through the combination of molecular synthesis, polymer science and supramolecular chemistry. This powerful toolbox allows us to shed new light on biological processes such as protein lipidation or phenotypic expression. Ultimately, our goal is to control complex biological phenomena such as membrane generation and organization, or the activation of multiple cellular signaling pathways, to gain new insights on important biomedical questions how live emerged on earth or how pathogens trigger infection.

Nanochemical Approaches to Deliver Functional Biomolecules

Our goal is to develop new nanocarriers capable of efficiently delivering the next generation of biomolecular therapies. By fabricating and modifying biomimetic nanomaterials and developing new chemical tools, we can program nanocarriers with properties like improved stability, enhanced targeting of cellular biomarkers, and responsive controlled release of therapeutic cargo. This will help underpin the efficient delivery of membrane active peptides and functional nucleic acids to target sites.